BAIT

L3MBTL2

H-l(3)mbt-l, L3MBT, RP4-756G23.4
l(3)mbt-like 2 (Drosophila)
GO Process (0)
GO Function (3)
GO Component (1)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

TCP1

CCT-alpha, CCT1, CCTa, D6S230E, TCP-1-alpha
t-complex 1
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

A High-Density Map for Navigating the Human Polycomb Complexome.

Hauri S, Comoglio F, Seimiya M, Gerstung M, Glatter T, Hansen K, Aebersold R, Paro R, Gstaiger M, Beisel C

Polycomb group (PcG) proteins are major determinants of gene silencing and epigenetic memory in higher eukaryotes. Here, we systematically mapped the human PcG complexome using a robust affinity purification mass spectrometry approach. Our high-density protein interaction network uncovered a diverse range of PcG complexes. Moreover, our analysis identified PcG interactors linking them to the PcG system, thus providing insight into ... [more]

Cell Rep Dec. 04, 2015; 17(2);583-595 [Pubmed: 27705803]

Throughput

  • High Throughput

Curated By

  • BioGRID