CDC7
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
SID2
Gene Ontology Biological Process
- maintenance of endoplasmic reticulum location involved in endoplasmic reticulum polarization at cell division site [IMP]
- negative regulation of protein homooligomerization [IMP]
- negative regulation of protein localization to microtubule [IMP]
- positive regulation of mitotic spindle elongation [IMP]
- positive regulation of nuclear migration during mitotic telophase [IMP]
- positive regulation of septation initiation signaling [IMP]
- regulation of mitotic cytokinesis [IMP]
- septation initiation signaling [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Synthetic Lethality
A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition.
Publication
Isolation and characterization of new fission yeast cytokinesis mutants.
Schizosaccharomyces pombe is an excellent organism in which to study cytokinesis as it divides by medial fission using an F-actin contractile ring. To enhance our understanding of the cell division process, a large genetic screen was carried out in which 17 genetic loci essential for cytokinesis were identified, 5 of which are novel. Mutants identifying three genes, rng3(+), rng4(+), and ... [more]
Throughput
- Low Throughput
Ontology Terms
- phenotype: inviable (APO:0000112)
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| SID2 CDC7 | Dosage Rescue Dosage Rescue A genetic interaction is inferred when over expression or increased dosage of one gene rescues the lethality or growth defect of a strain that is mutated or deleted for another gene. | Low | - | BioGRID | 672248 | |
| SID2 CDC7 | Synthetic Lethality Synthetic Lethality A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition. | Low | - | BioGRID | 796917 |
Curated By
- BioGRID