BAIT
PPP5C
PP5, PPP5, PPT
protein phosphatase 5, catalytic subunit
GO Process (4)
GO Function (5)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ELP3
KAT9
elongator acetyltransferase complex subunit 3
GO Process (9)
GO Function (5)
GO Component (5)
Gene Ontology Biological Process
- central nervous system development [ISS]
- chromatin organization [TAS]
- histone H3 acetylation [IDA]
- histone H4 acetylation [IDA]
- neuron migration [ISS]
- positive regulation of cell migration [ISS]
- regulation of protein kinase activity [IDA]
- regulation of transcription from RNA polymerase II promoter [IDA, TAS]
- transcription elongation from RNA polymerase II promoter [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.
Coordinated activities of protein kinases and phosphatases ensure phosphorylation homeostasis, which, when perturbed, can instigate diseases, including cancer. Yet, in contrast to kinases, much less is known about protein phosphatase functions and their interactions and complexes. Here, we used quantitative affinity proteomics to assay protein-protein interactions for 54 phosphatases distributed across the three major protein phosphatase families, with additional analysis ... [more]
Cell Syst Apr. 26, 2017; 4(4);430-444.e5 [Pubmed: 28330616]
Throughput
- High Throughput
Curated By
- BioGRID