BAIT
TNIP2
ABIN2, FLIP1, KLIP, RP3-474M20.1
TNFAIP3 interacting protein 2
GO Process (12)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
- CD40 signaling pathway [ISS]
- cellular response to lipopolysaccharide [ISS]
- interleukin-1-mediated signaling pathway [ISS]
- negative regulation of endothelial cell apoptotic process [IDA]
- positive regulation of B cell activation [ISS]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [IDA]
- positive regulation of macrophage activation [ISS]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- protein stabilization [ISS]
- toll-like receptor 2 signaling pathway [ISS]
- toll-like receptor 3 signaling pathway [ISS]
- toll-like receptor 9 signaling pathway [ISS]
Gene Ontology Molecular Function
Homo sapiens
PREY
DAG1
156DAG, A3a, AGRNR, DAG, MDDGC7, MDDGC9
dystroglycan 1 (dystrophin-associated glycoprotein 1)
GO Process (9)
GO Function (8)
GO Component (13)
Gene Ontology Biological Process
- NLS-bearing protein import into nucleus [IDA]
- cytoskeletal anchoring at plasma membrane [IMP]
- extracellular matrix organization [TAS]
- membrane protein ectodomain proteolysis [IDA]
- microtubule anchoring [IMP]
- modulation by virus of host morphology or physiology [IDA]
- negative regulation of MAPK cascade [IMP]
- negative regulation of cell migration [IMP]
- negative regulation of protein kinase B signaling [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- basement membrane [IDA]
- contractile ring [IDA]
- cytoplasm [IDA]
- dystrophin-associated glycoprotein complex [IDA]
- extracellular region [TAS]
- extracellular space [IDA]
- extracellular vesicular exosome [IDA]
- filopodium [IDA]
- focal adhesion [IDA]
- integral component of membrane [IDA]
- lamellipodium [IDA]
- nucleoplasm [IDA]
- plasma membrane [IDA, TAS]
Homo sapiens
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.
The NF-κB family of transcription factors is pivotal in controlling cellular responses to environmental stresses; abnormal nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling features in many autoimmune diseases and cancers. Several components of the NF-κB signaling pathway have been reported to interact with the protein TNIP2 (also known as ABIN2), and TNIP2 can both positively and negatively regulate ... [more]
Mol. Cell Proteomics Dec. 01, 2015; 15(11);3435-3449 [Pubmed: 27609421]
Throughput
- High Throughput
Curated By
- BioGRID