CCND2
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
CDK5
Gene Ontology Biological Process
- axon extension [TAS]
- axon guidance [TAS]
- blood coagulation [TAS]
- cell proliferation [TAS]
- negative regulation of neuron death [IDA]
- negative regulation of proteolysis [IMP]
- negative regulation of transcription, DNA-templated [IMP]
- neuron apoptotic process [TAS]
- neuron differentiation [ISS, TAS]
- neuron migration [TAS]
- neuron projection development [ISS]
- oligodendrocyte differentiation [IDA]
- peptidyl-serine phosphorylation [IDA]
- phosphorylation [IDA]
- positive regulation of actin cytoskeleton reorganization [TAS]
- positive regulation of neuron apoptotic process [ISS]
- regulation of apoptotic process [TAS]
- regulation of cell cycle arrest [TAS]
- regulation of dendritic spine morphogenesis [ISS]
- regulation of synaptic plasticity [ISS, TAS]
- regulation of synaptic vesicle recycling [NAS]
- synapse assembly [TAS]
- synaptic transmission [TAS]
- synaptic vesicle endocytosis [TAS]
- synaptic vesicle exocytosis [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Pooled-matrix protein interaction screens using Barcode Fusion Genetics.
High-throughput binary protein interaction mapping is continuing to extend our understanding of cellular function and disease mechanisms. However, we remain one or two orders of magnitude away from a complete interaction map for humans and other major model organisms. Completion will require screening at substantially larger scales with many complementary assays, requiring further efficiency gains in proteome-scale interaction mapping. Here, ... [more]
Throughput
- High Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| CDK5 CCND2 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 68 | BioGRID | 3483377 | |
| CCND2 CDK5 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.8591 | BioGRID | 1180504 | |
| CCND2 CDK5 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9584 | BioGRID | 2250205 | |
| CCND2 CDK5 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9732 | BioGRID | 3099620 | |
| CDK5 CCND2 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | 906815 | |
| CDK5 CCND2 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | 941299 | |
| CDK5 CCND2 | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | - | |
| CCND2 CDK5 | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | 2717601 | |
| CCND2 CDK5 | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | - | |
| CDK5 CCND2 | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | - |
Curated By
- BioGRID