BAIT
ULK2
ATG1B, Unc51.2
unc-51 like autophagy activating kinase 2
GO Process (5)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
SYNGAP1
MRD5, RASA1, RASA5, SYNGAP, DASS-97D12.6
synaptic Ras GTPase activating protein 1
GO Process (3)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Role of Unc51.1 and its binding partners in CNS axon outgrowth.
Previous studies showed that the serine/threonine kinase Unc51.1 is one of the earliest genes in neuronal differentiation and is required for granule cell axon formation. To examine the mechanism of Unc51.1 regulation of axon extension, we have identified two direct binding partners. The first, SynGAP, a negative regulator of Ras, is expressed within axons and growth cones of developing granule ... [more]
Genes Dev. Mar. 01, 2004; 18(5);541-58 [Pubmed: 15014045]
Throughput
- Low Throughput
Curated By
- BioGRID