BAIT

PPP1R13L

IASPP, NKIP1, RAI, RAI4
protein phosphatase 1, regulatory subunit 13 like
Human Papilloma Virus (HPV) Project
GO Process (0)
GO Function (3)
GO Component (3)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

MAPRE3

EB3, EBF3, EBF3-S, RP3
microtubule-associated protein, RP/EB family, member 3
Cell Cycle - Mitotic Spindle Assembly Project
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

iASPP-PP1 complex is required for cytokinetic abscission by controlling CEP55 dephosphorylation.

Gao K, Zhang Y, Shi Q, Zhang J, Zhang L, Sun H, Jiao D, Zhao X, Tao H, Wei Y, Wang Y, Saiyin H, Zhao SM, Li Y, Zhang P, Wang C

Cytokinesis is the last step of cell division and is concluded by the abscission of the intercellular bridge that connects two daughter cells. The tight regulation of cytokinesis completion is essential because cytokinesis failure is associated with various human diseases. Here, we report that iASPP, a member of the apoptosis-stimulating proteins of p53 (ASPP) family, is required for proper cell ... [more]

Cell Death Dis Dec. 01, 2017; 9(5);528 [Pubmed: 29743530]

Throughput

  • Low Throughput

Curated By

  • BioGRID