BAIT

INPP5D

SHIP, SHIP-1, SHIP1, SIP-145, hp51CN, p150Ship
inositol polyphosphate-5-phosphatase, 145kDa
Homo sapiens
PREY

FCGR2B

CD32, CD32B, FCG2, FCGR2, IGFR2, RP11-474I16.2
Fc fragment of IgG, low affinity IIb, receptor (CD32)
Alzheimer's Disease Project
GO Process (3)
GO Function (1)
GO Component (1)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Protein-peptide

An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.

Publication

Co-clustering of Fcgamma and B cell receptors induces dephosphorylation of the Grb2-associated binder 1 docking protein.

Koncz G, Toth GK, Boekoenyi G, Keri G, Pecht I, Medgyesi D, Gergely J, Sarmay G

The immunoreceptor tyrosine-based inhibitory motif (ITIM) of human type IIb Fcgamma receptor (FcgammaRIIb) is phosphorylated on its tyrosine upon co-clustering with the B cell receptor (BCR). The phosphorylated ITIM (p-ITIM) binds to the SH2 domains of polyphosphoinositol 5-phosphatase (SHIP) and the tyrosine phosphatase, SHP-2. We investigated the involvement of the molecular complex composed of the phosphorylated SHIP and FcgammaRIIb in ... [more]

Eur. J. Biochem. Jul. 01, 2001; 268(14);3898-906 [Pubmed: 11453982]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
INPP5D FCGR2B
Protein-peptide
Protein-peptide

An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.

Low-BioGRID
-

Curated By

  • BioGRID