BAIT
HIST1H3A
H3/A, H3FA
histone cluster 1, H3a
GO Process (4)
GO Function (1)
GO Component (7)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
CYP1B1
CP1B, CYPIB1, GLC3A, P4501B1
cytochrome P450, family 1, subfamily B, polypeptide 1
GO Process (32)
GO Function (4)
GO Component (2)
Gene Ontology Biological Process
- arachidonic acid metabolic process [IDA, TAS]
- blood vessel morphogenesis [ISS]
- cell adhesion [ISS]
- cellular response to hydrogen peroxide [ISS]
- cellular response to organic cyclic compound [IDA]
- collagen fibril organization [ISS]
- endothelial cell migration [ISS]
- epoxygenase P450 pathway [TAS]
- estrogen metabolic process [IDA]
- intrinsic apoptotic signaling pathway in response to oxidative stress [ISS]
- membrane lipid catabolic process [ISS]
- negative regulation of NF-kappaB transcription factor activity [ISS]
- negative regulation of cell adhesion mediated by integrin [ISS]
- negative regulation of cell migration [ISS]
- negative regulation of cell proliferation [ISS]
- nitric oxide biosynthetic process [ISS]
- omega-hydroxylase P450 pathway [TAS]
- oxidation-reduction process [TAS]
- positive regulation of JAK-STAT cascade [ISS]
- positive regulation of angiogenesis [ISS]
- positive regulation of apoptotic process [ISS]
- positive regulation vascular endothelial growth factor production [ISS]
- regulation of reactive oxygen species metabolic process [ISS]
- retinal blood vessel morphogenesis [ISS]
- retinal metabolic process [IDA]
- retinol metabolic process [IDA]
- small molecule metabolic process [TAS]
- steroid metabolic process [IDA]
- sterol metabolic process [TAS]
- trabecular meshwork development [ISS]
- visual perception [TAS]
- xenobiotic metabolic process [IDA, TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-localization
Interaction inferred from two proteins that co-localize in the cell by indirect immunofluorescence only when in addition, if one gene is deleted, the other protein becomes mis-localized. Also includes co-dependent association of proteins with promoter DNA in chromatin immunoprecipitation experiments.
Publication
Aryl hydrocarbon receptor (AHR) regulation of L-Type Amino Acid Transporter 1 (LAT-1) expression in MCF-7 and MDA-MB-231 breast cancer cells.
The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that is regulated by environmental toxicants that function as AHR agonists such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). L-Type Amino Acid Transporter 1 (LAT1) is a leucine transporter that is overexpressed in cancer. The regulation of LAT1 by AHR in MCF-7 and MDA-MB-231 breast cancer cells (BCCs) was investigated in this report. Ingenuity ... [more]
Biochem. Pharmacol. Apr. 15, 2016; 106();94-103 [Pubmed: 26944194]
Throughput
- Low Throughput
Additional Notes
- ChIP
Curated By
- BioGRID