BAIT
DRD3
D3DR, ETM1, FET1
dopamine receptor D3
GO Process (33)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
- G-protein coupled receptor internalization [IDA]
- G-protein coupled receptor signaling pathway [IDA]
- acid secretion [ISS]
- adenylate cyclase-activating dopamine receptor signaling pathway [IDA]
- adenylate cyclase-inhibiting dopamine receptor signaling pathway [IDA]
- arachidonic acid secretion [IDA]
- behavioral response to cocaine [IEP, ISS]
- cellular calcium ion homeostasis [IDA]
- circadian regulation of gene expression [ISS]
- dopamine metabolic process [IC]
- learning [NAS]
- learning or memory [NAS]
- locomotory behavior [ISS]
- musculoskeletal movement, spinal reflex action [ISS]
- negative regulation of adenylate cyclase activity [IDA]
- negative regulation of blood pressure [ISS]
- negative regulation of oligodendrocyte differentiation [ISS]
- negative regulation of protein kinase B signaling [ISS]
- negative regulation of protein secretion [IDA]
- positive regulation of cytokinesis [IMP]
- positive regulation of dopamine receptor signaling pathway [ISS]
- positive regulation of mitosis [ISS]
- prepulse inhibition [IMP]
- regulation of cAMP metabolic process [IDA]
- regulation of dopamine secretion [ISS]
- regulation of dopamine uptake involved in synaptic transmission [IC]
- response to cocaine [IEP]
- response to drug [ISS]
- response to ethanol [ISS]
- response to histamine [IDA]
- response to morphine [ISS]
- social behavior [NAS]
- visual learning [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
RDX
DFNB24
radixin
GO Process (2)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
CLIC6, a member of the intracellular chloride channel family, interacts with dopamine D(2)-like receptors.
To identify proteins interacting with the C-terminal cytoplasmic tail of the dopamine D(3) receptor (D(3)R), we used the two-hybrid system to screen a rat brain cDNA library. We isolated three partial cDNAs encoding, respectively, for the MUPP1 multi-PDZ protein, for the N-terminal region of radixin, for GIPC and for a 160-amino acid open reading frame sharing high homology with the ... [more]
Brain Res. Mol. Brain Res. Sep. 10, 2003; 117(1);47-57 [Pubmed: 14499480]
Throughput
- Low Throughput
Curated By
- BioGRID