BAIT
SRI
CP-22, CP22, SCN, V19
sorcin
GO Process (17)
GO Function (8)
GO Component (10)
Gene Ontology Biological Process
- action potential [TAS]
- intracellular sequestering of iron ion [TAS]
- muscle organ development [TAS]
- negative regulation of heart rate [IMP]
- negative regulation of ryanodine-sensitive calcium-release channel activity [IDA]
- proteolysis [IBA]
- regulation of calcium ion transport [IMP]
- regulation of cardiac muscle cell contraction [IMP]
- regulation of cell communication by electrical coupling [TAS]
- regulation of cell communication by electrical coupling involved in cardiac conduction [IMP]
- regulation of heart contraction [TAS]
- regulation of high voltage-gated calcium channel activity [IMP]
- regulation of relaxation of muscle [IMP]
- regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [TAS]
- regulation of striated muscle contraction [TAS]
- signal transduction [TAS]
- transport [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ALG2
CDGIi, NET38, hALPG2, RP11-13B9.1
ALG2, alpha-1,3/1,6-mannosyltransferase
GO Process (7)
GO Function (5)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
The PEF family proteins sorcin and grancalcin interact in vivo and in vitro.
The penta-EF hand (PEF) family of calcium binding proteins includes grancalcin, peflin, sorcin, calpain large and small subunits as well as ALG-2. Systematic testing of the heterodimerization abilities of the PEF proteins using the yeast two-hybrid and glutathione S-transferase pull-down assays revealed the new finding that grancalcin interacts strongly with sorcin. In addition, sorcin and grancalcin can be co-immunoprecipitated from ... [more]
FEBS Lett. Jun. 19, 2003; 545(2);151-4 [Pubmed: 12804766]
Throughput
- Low Throughput
Curated By
- BioGRID