BAIT
PHB
HEL-215, HEL-S-54e, PHB1
prohibitin
GO Process (15)
GO Function (4)
GO Component (8)
Gene Ontology Biological Process
- cellular response to interleukin-6 [IDA]
- histone deacetylation [IDA]
- negative regulation of androgen receptor signaling pathway [IDA, IMP]
- negative regulation of cell growth [IMP]
- negative regulation of cell proliferation [IMP]
- negative regulation of glucocorticoid receptor signaling pathway [IDA]
- negative regulation of transcription by competitive promoter binding [IDA]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- negative regulation of transcription, DNA-templated [IDA, IMP]
- osteoblast differentiation [IDA]
- positive regulation of transcription, DNA-templated [IDA]
- progesterone receptor signaling pathway [IDA]
- regulation of apoptotic process [TAS]
- regulation of transcription, DNA-templated [IDA]
- signal transduction [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
EIF4G1
EIF-4G1, EIF4F, EIF4G, EIF4GI, P220, PARK18
eukaryotic translation initiation factor 4 gamma, 1
GO Process (12)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- cellular protein metabolic process [TAS]
- cytokine-mediated signaling pathway [TAS]
- gene expression [TAS]
- insulin receptor signaling pathway [TAS]
- mRNA metabolic process [TAS]
- nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [TAS]
- nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [TAS]
- nuclear-transcribed mRNA poly(A) tail shortening [TAS]
- regulation of translational initiation [IMP, NAS]
- translation [TAS]
- translational initiation [TAS]
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Prohibitin 1 regulates tumor cell apoptosis via the interaction with X-linked inhibitor of apoptosis protein.
... [more]
J Mol Cell Biol Dec. 01, 2015; 8(3);282-5 [Pubmed: 27025967]
Throughput
- High Throughput
Curated By
- BioGRID