BAIT
TGM2
G-ALPHA-h, GNAH, HEL-S-45, TG2, TGC, RP5-1054A22.2
transglutaminase 2
GO Process (5)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
CYC1
MC3DN6, UQCR4
cytochrome c-1
GO Process (3)
GO Function (1)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Transglutaminase Type 2 Regulates ER-Mitochondria Contact Sites by Interacting with GRP75.
Transglutaminase type 2 (TG2) is a multifunctional enzyme that plays a key role in mitochondria homeostasis under stressful cellular conditions. TG2 interactome analysis reveals an enzyme interaction with GRP75 (glucose-regulated protein 75). GRP75 localizes in mitochondria-associated membranes (MAMs) and acts as a bridging molecule between the two organelles by assembling the IP3R-GRP75-VDAC complex, which is involved in the transport of ... [more]
Cell Rep Dec. 26, 2017; 25(13);3573-3581.e4 [Pubmed: 30590033]
Throughput
- High Throughput
Curated By
- BioGRID