BAIT

FOXRED1

H17, FP634
FAD-dependent oxidoreductase domain containing 1
GO Process (0)
GO Function (0)
GO Component (1)

Gene Ontology Cellular Component

Homo sapiens
PREY

NDUFB10

PDSW
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Characterization of mitochondrial FOXRED1 in the assembly of respiratory chain complex I.

Formosa LE, Mimaki M, Frazier AE, McKenzie M, Stait TL, Thorburn DR, Stroud DA, Ryan MT

Human mitochondrial complex I is the largest enzyme of the respiratory chain and is composed of 44 different subunits. Complex I subunits are encoded by both nuclear and mitochondrial (mt) DNA and their assembly requires a number of additional proteins. FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) was recently identified as a putative assembly factor and FOXRED1 mutations in patients cause ... [more]

Hum. Mol. Genet. May. 15, 2015; 24(10);2952-65 [Pubmed: 25678554]

Throughput

  • High Throughput

Curated By

  • BioGRID