BAIT

SULT4A1

BR-STL-1, BRSTL1, DJ388M5.3, NST, SULTX3, hBR-STL-1
sulfotransferase family 4A, member 1
GO Process (3)
GO Function (2)
GO Component (1)
Homo sapiens
PREY

MAPK3

ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK
mitogen-activated protein kinase 3
GO Process (52)
GO Function (3)
GO Component (12)

Gene Ontology Biological Process

Homo sapiens

Biochemical Activity (Phosphorylation)

An interaction is inferred from the biochemical effect of one protein upon another, for example, GTP-GDP exchange activity or phosphorylation of a substrate by a kinase. The bait protein executes the activity on the substrate hit protein. A Modification value is recorded for interactions of this type with the possible values Phosphorylation, Ubiquitination, Sumoylation, Dephosphorylation, Methylation, Prenylation, Acetylation, Deubiquitination, Proteolytic Processing, Glucosylation, Nedd(Rub1)ylation, Deacetylation, No Modification, Demethylation.

Publication

Phosphorylation/dephosphorylation of human SULT4A1: role of Erk1 and PP2A.

Mitchell DJ, Butcher NJ, Minchin RF

SULT4A1 is a cytosolic sulfotransferase that shares little homology with other human sulfotransferases but is highly conserved between species. It is found in neurons located in several regions of the brain. Recently, the stability of SULT4A1 was shown to be regulated by Pin1, a peptidyl-prolyl cis-trans isomerase implicated in several neurodegenerative diseases. Since Pin1 binds preferentially to phosphoproteins, these findings ... [more]

Biochim. Biophys. Acta Jan. 01, 2011; 1813(1);231-7 [Pubmed: 20920535]

Throughput

  • Low Throughput

Curated By

  • BioGRID