BAIT
MGST1
GST12, MGST, MGST-I
microsomal glutathione S-transferase 1
GO Process (6)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
LAMTOR1
C11orf59, PDRO, Ragulator1, p18, p27RF-Rho, PP7157
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
GO Process (15)
GO Function (3)
GO Component (8)
Gene Ontology Biological Process
- cell growth [IMP]
- cellular protein localization [IMP]
- cellular response to amino acid stimulus [IMP]
- cholesterol homeostasis [IMP]
- endosome localization [ISS]
- endosome organization [ISS]
- lysosome localization [ISS]
- lysosome organization [ISS]
- positive regulation of GTPase activity [IDA]
- positive regulation of MAPK cascade [ISS]
- positive regulation of TOR signaling [IMP]
- regulation of cholesterol efflux [IMP]
- regulation of cholesterol esterification [IMP]
- regulation of cholesterol import [IMP]
- regulation of receptor recycling [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis.
Mitochondrial protein (MP) assemblies undergo alterations during neurogenesis, a complex process vital in brain homeostasis and disease. Yet which MP assemblies remodel during differentiation remains unclear. Here, using mass spectrometry-based co-fractionation profiles and phosphoproteomics, we generated mitochondrial interaction maps of human pluripotent embryonal carcinoma stem cells and differentiated neuronal-like cells, which presented as two discrete cell populations by single-cell RNA ... [more]
iScience Sep. 27, 2019; 19();1114-1132 [Pubmed: 31536960]
Quantitative Score
- 1.527124839 [Confidence Score]
Throughput
- High Throughput
Additional Notes
- Protein pairs with Sigma LLS score >= 1.45 derived from Ntera2 embryonic carcinoma stem cells (ECSC)
Curated By
- BioGRID