BAIT
MS4A4A
4SPAN1, CD20-L1, CD20L1, MS4A4, MS4A7, HDCME31P
membrane-spanning 4-domains, subfamily A, member 4A
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
AGPAT2
1-AGPAT2, BSCL, BSCL1, LPAAB, LPAAT-beta
1-acylglycerol-3-phosphate O-acyltransferase 2
GO Process (8)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
- cellular lipid metabolic process [TAS]
- glycerophospholipid biosynthetic process [TAS]
- phosphatidic acid biosynthetic process [IGI, TAS]
- phospholipid metabolic process [NAS, TAS]
- positive regulation of cytokine production [IMP]
- positive regulation of cytokine-mediated signaling pathway [IC]
- small molecule metabolic process [TAS]
- triglyceride biosynthetic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.
Interferon-stimulated genes (ISGs) form the backbone of the innate immune system and are important for limiting intra- and intercellular viral replication and spread. We conducted a mass-spectrometry-based survey to understand the fundamental organization of the innate immune system and to explore the molecular functions of individual ISGs. We identified interactions between 104 ISGs and 1,401 cellular binding partners engaging in ... [more]
Nat. Immunol. Dec. 01, 2018; 20(4);493-502 [Pubmed: 30833792]
Throughput
- High Throughput
Curated By
- BioGRID