BAIT
PHPT1
CGI-202, HEL-S-132P, HSPC141, PHP14, RP11-216L13.10-005
phosphohistidine phosphatase 1
GO Process (7)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
- negative regulation of ATP citrate synthase activity [IDA]
- negative regulation of T cell receptor signaling pathway [IMP]
- negative regulation of lyase activity [IDA]
- peptidyl-histidine dephosphorylation [IDA]
- positive regulation of cell motility [IMP]
- protein dephosphorylation [IDA]
- regulation of actin cytoskeleton reorganization [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
AASDHPPT
AASD-PPT, LYS2, LYS5, CGI-80
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
GO Process (4)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.
Tyrosine phosphatases play a critical role in many cellular processes and pathogenesis, yet comprehensive analysis of their functional interacting proteins in the cell is limited. By utilizing a proteomic approach, here we present an interaction network of 81 human tyrosine phosphatases built on 1884 high-confidence interactions of which 85% are unreported. Our analysis has linked several phosphatases with new cellular ... [more]
J. Proteome Res. Dec. 04, 2016; 16(8);2789-2801 [Pubmed: 28675297]
Throughput
- High Throughput
Curated By
- BioGRID