BAIT

EYA4

CMD1J, DFNA10, RP11-704J17.4
EYA transcriptional coactivator and phosphatase 4
GO Process (2)
GO Function (1)
GO Component (0)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Homo sapiens
PREY

KCTD12

C13orf2, PFET1, PFETIN
potassium channel tetramerization domain containing 12
UPS Project
GO Process (0)
GO Function (1)
GO Component (1)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

Kumar P, Munnangi P, Chowdary KR, Shah VJ, Shinde SR, Kolli NR, Halehalli RR, Nagarajaram HA, Maddika S

Tyrosine phosphatases play a critical role in many cellular processes and pathogenesis, yet comprehensive analysis of their functional interacting proteins in the cell is limited. By utilizing a proteomic approach, here we present an interaction network of 81 human tyrosine phosphatases built on 1884 high-confidence interactions of which 85% are unreported. Our analysis has linked several phosphatases with new cellular ... [more]

J. Proteome Res. Dec. 04, 2016; 16(8);2789-2801 [Pubmed: 28675297]

Throughput

  • High Throughput

Curated By

  • BioGRID