BAIT

CYLD

BRSS, CDMT, CYLD1, CYLDI, EAC, MFT, MFT1, SBS, TEM, USPL2, HSPC057
cylindromatosis (turban tumor syndrome)
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

CYLD Regulates Centriolar Satellites Proteostasis by Counteracting the E3 Ligase MIB1.

Douanne T, Andre-Gregoire G, Thys A, Trillet K, Gavard J, Bidere N

The tumor suppressor CYLD is a deubiquitinating enzyme that removes non-degradative ubiquitin linkages bound to a variety of signal transduction adaptors. CYLD participates in the formation of primary cilia, a microtubule-based structure that protrudes from the cell body to act as a "sensing antenna." Yet, how exactly CYLD regulates ciliogenesis is not fully understood. Here, we conducted an unbiased proteomic ... [more]

Cell Rep Dec. 07, 2018; 27(6);1657-1665.e4 [Pubmed: 31067453]

Throughput

  • High Throughput

Curated By

  • BioGRID