TRIP12
Gene Ontology Biological Process
Gene Ontology Molecular Function
SOX6
Gene Ontology Biological Process
- astrocyte differentiation [ISO]
- cardiac muscle cell differentiation [IDA]
- cartilage development [IGI]
- cell fate commitment [IGI]
- cell morphogenesis [IMP]
- cellular response to transforming growth factor beta stimulus [ISO]
- erythrocyte development [IMP]
- erythrocyte differentiation [IMP]
- gene silencing [IMP]
- hemopoiesis [IMP]
- in utero embryonic development [IMP]
- muscle cell differentiation [IDA]
- negative regulation of transcription from RNA polymerase II promoter [IDA, IMP]
- negative regulation of transcription, DNA-templated [IDA]
- oligodendrocyte cell fate specification [IMP]
- oligodendrocyte differentiation [IMP]
- positive regulation of cartilage development [ISO]
- positive regulation of chondrocyte differentiation [IDA, ISO]
- positive regulation of mesenchymal stem cell differentiation [ISO]
- positive regulation of transcription from RNA polymerase II promoter [IGI]
- positive regulation of transcription, DNA-templated [IDA]
- post-embryonic development [IMP]
- regulation of gene expression [IMP]
- regulation of transcription, DNA-templated [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Quantitative Score
- 0.941 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| TRIP12 SOX6 | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | - |
Curated By
- BioGRID