Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

The zinc finger-associated SCAN box is a conserved oligomerization domain.

Williams AJ, Blacklow SC, Collins T

A number of Cys(2)His(2) zinc finger proteins contain a highly conserved amino-terminal motif termed the SCAN domain. This element is an 80-residue, leucine-rich region that contains three segments strongly predicted to be alpha-helices. In this report, we show that the SCAN motif functions as an oligomerization domain mediating self-association or association with other proteins bearing SCAN domains. These findings suggest ... [more]

Mol. Cell. Biol. Dec. 01, 1999; 19(12);8526-35 [Pubmed: 10567577]

Throughput

Low Throughput

Related interactions

Interaction	Experimental Evidence Code	Dataset	Throughput	Score	Curated By	Notes
ZNF174 ZNF174	Reconstituted Complex Reconstituted Complex An interaction is detected between purified proteins in vitro.	Stone JR (2002)	Low	-	BioGRID	-

Curated By

BioGRID

Interaction Summary

ZNF174

Gene Ontology Biological Process

Gene Ontology Molecular Function

protein homodimerization activity [IPI]sequence-specific DNA binding RNA polymerase II transcription factor activity [IBA]sequence-specific DNA binding transcription factor activity [IDA]transcription regulatory region DNA binding [IDA]

Gene Ontology Cellular Component