BAIT
MGLL
HU-K5, HUK5, MAGL, MGL
monoglyceride lipase
GO Process (15)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
- acylglycerol acyl-chain remodeling [TAS]
- acylglycerol catabolic process [ISS]
- arachidonic acid metabolic process [ISS]
- blood coagulation [TAS]
- glycerophospholipid biosynthetic process [TAS]
- inflammatory response [TAS]
- lipid metabolic process [TAS]
- phospholipid metabolic process [TAS]
- platelet activation [TAS]
- regulation of endocannabinoid signaling pathway [ISS]
- regulation of inflammatory response [ISS]
- regulation of sensory perception of pain [ISS]
- regulation of signal transduction [ISS]
- small molecule metabolic process [TAS]
- triglyceride catabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
STOM
BND7, EPB7, EPB72, RP11-342H3.1
stomatin
GO Process (1)
GO Function (0)
GO Component (9)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A reference map of the human binary protein interactome.
Global insights into cellular organization and genome function require comprehensive understanding of the interactome networks that mediate genotype-phenotype relationships1,2. Here we present a human 'all-by-all' reference interactome map of human binary protein interactions, or 'HuRI'. With approximately 53,000 protein-protein interactions, HuRI has approximately four times as many such interactions as there are high-quality curated interactions from small-scale studies. The integration ... [more]
Nature Apr. 01, 2020; 580(7803);402-408 [Pubmed: 32296183]
Throughput
- High Throughput
Additional Notes
- This human reference interactome (HuRI) was generated by performing nine two-hybrid screens with the high confidence interactions determined by pairwise verification by quadruplicate retesting and sequence confirmation. This HI-III-20 dataset contains over 52,000 PPIs involving more than 8,000 proteins.
Curated By
- BioGRID