BAIT
GOSR2
Bos1, EPM6, GS27
golgi SNAP receptor complex member 2
GO Process (10)
GO Function (3)
GO Component (7)
Gene Ontology Biological Process
- ER to Golgi vesicle-mediated transport [IBA]
- Golgi to vacuole transport [IBA]
- activation of signaling protein activity involved in unfolded protein response [TAS]
- cellular protein metabolic process [TAS]
- endoplasmic reticulum unfolded protein response [TAS]
- intra-Golgi vesicle-mediated transport [IBA]
- membrane fusion [TAS]
- protein targeting to vacuole [IBA]
- retrograde transport, endosome to Golgi [IBA]
- vesicle fusion with Golgi apparatus [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
LIME1
LIME, LP8067, dJ583P15.4, RP4-583P15.5
Lck interacting transmembrane adaptor 1
GO Process (0)
GO Function (0)
GO Component (1)
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A reference map of the human binary protein interactome.
Global insights into cellular organization and genome function require comprehensive understanding of the interactome networks that mediate genotype-phenotype relationships1,2. Here we present a human 'all-by-all' reference interactome map of human binary protein interactions, or 'HuRI'. With approximately 53,000 protein-protein interactions, HuRI has approximately four times as many such interactions as there are high-quality curated interactions from small-scale studies. The integration ... [more]
Nature Apr. 01, 2020; 580(7803);402-408 [Pubmed: 32296183]
Throughput
- High Throughput
Additional Notes
- This human reference interactome (HuRI) was generated by performing nine two-hybrid screens with the high confidence interactions determined by pairwise verification by quadruplicate retesting and sequence confirmation. This HI-III-20 dataset contains over 52,000 PPIs involving more than 8,000 proteins.
Curated By
- BioGRID