BAIT
PRKRA
DYT16, PACT, RAX, HSD14
protein kinase, interferon-inducible double stranded RNA dependent activator
GO Process (6)
GO Function (4)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
GDF9
growth differentiation factor 9
GO Process (10)
GO Function (2)
GO Component (1)
Gene Ontology Biological Process
- BMP signaling pathway [IBA]
- SMAD protein signal transduction [IBA]
- cell development [IBA]
- female gamete generation [TAS]
- positive regulation of cell proliferation [IDA]
- positive regulation of pathway-restricted SMAD protein phosphorylation [IBA]
- regulation of MAPK cascade [IBA]
- regulation of apoptotic process [IBA]
- regulation of progesterone secretion [IDA, IMP]
- transforming growth factor beta receptor signaling pathway [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A human protein-protein interaction network: a resource for annotating the proteome.
Protein-protein interaction maps provide a valuable framework for a better understanding of the functional organization of the proteome. To detect interacting pairs of human proteins systematically, a protein matrix of 4456 baits and 5632 preys was screened by automated yeast two-hybrid (Y2H) interaction mating. We identified 3186 mostly novel interactions among 1705 proteins, resulting in a large, highly connected network. ... [more]
Cell Sep. 23, 2005; 122(6);957-68 [Pubmed: 16169070]
Quantitative Score
- 3.0 [Confidence Score]
Throughput
- High Throughput
Curated By
- BioGRID