BAIT
SNTA1
LQT12, SNT1, TACIP1, dJ1187J4.5
syntrophin, alpha 1
GO Process (6)
GO Function (5)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
GLS
AAD20, GAC, GAM, GLS1, KGA
glutaminase
GO Process (9)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
- cellular amino acid biosynthetic process [TAS]
- cellular nitrogen compound metabolic process [TAS]
- glutamate biosynthetic process [IDA, TAS]
- glutamate secretion [TAS]
- glutamine catabolic process [IDA, NAS]
- neurotransmitter secretion [TAS]
- protein homotetramerization [IDA]
- small molecule metabolic process [TAS]
- synaptic transmission [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
The C-terminus of human glutaminase L mediates association with PDZ domain-containing proteins.
The enzyme glutaminase in brain is responsible for the synthesis of neurotransmitter glutamate. We used the two-hybrid genetic selection system in yeast to look for interactors of glutaminase in human brain. We have identified two proteins containing PDZ domains, alpha1-syntrophin and a glutaminase-interacting protein, named GIP, that showed association with human glutaminase L, as deduced from specificity test of the ... [more]
FEBS Lett. Jan. 19, 2001; 488(3);116-22 [Pubmed: 11163757]
Throughput
- Low Throughput
Related interactions
Curated By
- BioGRID