BAIT

ST14

ARCI11, HAI, MT-SP1, MTSP1, PRSS14, SNC19, TADG15, TMPRSS14
suppression of tumorigenicity 14 (colon carcinoma)
Cell Cycle - Mitotic Spindle Assembly Project
GO Process (2)
GO Function (1)
GO Component (3)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

SPINT1

HAI, HAI1, MANSC2, UNQ223/PRO256
serine peptidase inhibitor, Kunitz type 1
GO Process (1)
GO Function (0)
GO Component (4)

Gene Ontology Biological Process

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Purification and characterization of a complex containing matriptase and a Kunitz-type serine protease inhibitor from human milk.

Lin CY, Anders J, Johnson M, Dickson RB

Matriptase, a trypsin-like serine protease with two potential regulatory modules (low density lipoprotein receptor and complement C1r/s domains), was initially purified from T-47D breast cancer cells. Given its plasma membrane localization, extracellular matrix-degrading activity, and expression by breast cancer cells, this protease may be involved in multiple aspects of breast tumor progression, including cancer invasion. In breast cancer cells, matriptase ... [more]

J. Biol. Chem. Jun. 25, 1999; 274(26);18237-42 [Pubmed: 10373425]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
ST14 SPINT1
Affinity Capture-MS
Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

High0.9823BioGRID
3245307

Curated By

  • BioGRID