BAIT

RAB11FIP4

RAB11-FIP4
RAB11 family interacting protein 4 (class II)
GO Process (1)
GO Function (4)
GO Component (6)
Homo sapiens
PREY

RAB11A

YL8
RAB11A, member RAS oncogene family
GO Process (24)
GO Function (7)
GO Component (12)
Homo sapiens

Far Western

An interaction is detected between a protein immobilized on a membrane and a purified protein probe.

Publication

Rab11-FIP4 interacts with Rab11 in a GTP-dependent manner and its overexpression condenses the Rab11 positive compartment in HeLa cells.

Wallace DM, Lindsay AJ, Hendrick AG, McCaffrey MW

We have recently identified Rab11-FIP4 as the sixth member of the Rab11-FIP family of Rab11 interacting proteins. Here, we demonstrate that Rab11-FIP4 interacts with Rab11 in a GTP-dependent manner and that its C-terminal region allows the protein to self-interact and interact with pp75/Rip11, Rab11-FIP2, and Rab11-FIP3. However, Rab11-FIP4 does not appear to interact directly with Rab coupling protein (RCP). We ... [more]

Biochem. Biophys. Res. Commun. Dec. 20, 2002; 299(5);770-9 [Pubmed: 12470645]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
RAB11FIP4 RAB11A
Reconstituted Complex
Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Low-BioGRID
-
RAB11FIP4 RAB11A
Two-hybrid
Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Low-BioGRID
-

Curated By

  • BioGRID