An interaction is inferred from the identification of two or more protein subunits in a purified protein complex, as obtained by classical biochemical fractionation or affinity purification and one or more additional fractionation steps.

Publication

S100A13 is involved in the regulation of fibroblast growth factor-1 and p40 synaptotagmin-1 release in vitro.

Mouta Carreira C, LaVallee TM, Tarantini F, Jackson A, Lathrop JT, Hampton B, Burgess WH, Maciag T

We have previously characterized the release of the signal peptide sequence-less fibroblast growth factor (FGF) prototype, FGF-1, in vitro as a stress-induced pathway in which FGF-1 is released as a latent homodimer with the p40 extravesicular domain of p65 synaptotagmin (Syn)-1. To determine the biologic relevance of the FGF-1 release pathway in vivo, we sought to resolve and characterize from ... [more]

J. Biol. Chem. Aug. 28, 1998; 273(35);22224-31 [Pubmed: 9712836]

Throughput

Low Throughput

Additional Notes

All proteins are from pig

Related interactions

Interaction	Experimental Evidence Code	Dataset	Throughput	Score	Curated By	Notes
S100A13 SYT1	Reconstituted Complex Reconstituted Complex An interaction is detected between purified proteins in vitro.	Landriscina M (2001)	Low	-	BioGRID	-

Curated By

BioGRID

Interaction Summary

S100A13

Gene Ontology Biological Process

Gene Ontology Molecular Function

RAGE receptor binding [IPI]calcium ion binding [IDA]copper ion binding [IDA]fibroblast growth factor binding [IPI]protein binding [IPI]protein homodimerization activity [IPI]zinc ion binding [IDA]

Gene Ontology Cellular Component

SYT1

Gene Ontology Biological Process

Gene Ontology Molecular Function

1-phosphatidylinositol binding [TAS]SNARE binding [ISS]calcium-dependent phospholipid binding [ISS, TAS]low-density lipoprotein particle receptor binding [IDA]protein binding [IPI]syntaxin-1 binding [ISS, TAS]