BAIT

KRT19P3

keratin 19 pseudogene 3
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY

COPS7A

CSN7, CSN7A, SGN7a
COP9 signalosome subunit 7A
UPS Project
GO Process (1)
GO Function (0)
GO Component (3)

Gene Ontology Biological Process

Gene Ontology Cellular Component

Homo sapiens

Protein-peptide

An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.

Publication

Long non-coding RNA KRT19P3 suppresses proliferation and metastasis through COPS7A-mediated NF-?B pathway in gastric cancer.

Zheng J, Zhang H, Ma R, Liu H, Gao P

Long non-coding RNAs (lncRNAs) have emerged as critical regulators in gastric cancer (GC). LncRNA expression microarray data indicate that KRT19P3 (Keratin 19 Pseudogene 3) is downregulated in GC samples. However, the expression pattern and molecular mechanism of KRT19P3 in GC have not been characterized. The present study confirmed the downregulation of KRT19P3 in GC tissues and cells. Decreased expression of ... [more]

Oncogene Dec. 01, 2018; 38(45);7073-7088 [Pubmed: 31409899]

Throughput

  • Low Throughput

Additional Notes

  • biotinylated RNA corresponding to the bait gene, KRT19P3, was precipitated after mixing with cell lysate and the protein corresponding to the hit gene, COPS7A, was identified as an associated protein by both MS (mass spectrometry) and western blotting

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
COPS7A KRT19P3
Affinity Capture-RNA
Affinity Capture-RNA

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.

Low-BioGRID
2768033

Curated By

  • BioGRID