PER1
Gene Ontology Biological Process
- circadian regulation of gene expression [IDA]
- circadian regulation of translation [ISS]
- circadian rhythm [IEP]
- entrainment of circadian clock [TAS]
- entrainment of circadian clock by photoperiod [ISS]
- histone H3 acetylation [IDA]
- histone H3 deacetylation [ISS]
- histone H4 acetylation [IDA]
- negative regulation of I-kappaB kinase/NF-kappaB signaling [ISS]
- negative regulation of JNK cascade [ISS]
- negative regulation of glucocorticoid receptor signaling pathway [ISS]
- negative regulation of transcription from RNA polymerase II promoter [ISS]
- negative regulation of transcription, DNA-templated [ISS]
- positive regulation of transcription from RNA polymerase II promoter [ISS]
- posttranscriptional regulation of gene expression [ISS]
- regulation of circadian rhythm [ISS]
- regulation of cytokine production involved in inflammatory response [ISS]
- regulation of hair cycle [IMP]
- regulation of p38MAPK cascade [ISS]
- regulation of sodium ion transport [ISS]
Gene Ontology Molecular Function
CSNK1D
Gene Ontology Biological Process
- DNA repair [TAS]
- G2/M transition of mitotic cell cycle [TAS]
- circadian regulation of gene expression [ISS]
- endocytosis [IBA]
- mitotic cell cycle [TAS]
- peptidyl-serine phosphorylation [IBA]
- positive regulation of canonical Wnt signaling pathway [IMP]
- positive regulation of proteasomal ubiquitin-dependent protein catabolic process [ISS]
- positive regulation of protein phosphorylation [IMP]
- protein phosphorylation [IDA]
- regulation of cell shape [IBA]
- regulation of circadian rhythm [ISS]
- signal transduction [TAS]
- spindle assembly [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Human casein kinase Idelta phosphorylation of human circadian clock proteins period 1 and 2.
Casein kinase Iepsilon (CKIepsilon), a central component of the circadian clock, interacts with and phosphorylates human period protein 1 (hPER1) [Keesler, G.A. et al. (2000) NeuroReport 5, 951-955]. A mutation in CKIepsilon causes a shortened circadian period in Syrian Golden hamster. We have now extended our previous studies to show that human casein kinase Idelta (hCKIdelta), the closest homologue to ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| CSNK1D PER1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 1428 | BioGRID | 3482226 | |
| CSNK1D PER1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 1 | BioGRID | 2224876 | |
| CSNK1D PER1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 1 | BioGRID | 3097202 |
Curated By
- BioGRID