BAIT
TRIM6
RNF89
tripartite motif containing 6
GO Process (1)
GO Function (0)
GO Component (1)
Gene Ontology Biological Process
Homo sapiens
PREY
SLC25A5
2F1, AAC2, ANT2, T2, T3
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
GO Process (8)
GO Function (3)
GO Component (8)
Gene Ontology Biological Process
- adenine transport [TAS]
- energy reserve metabolic process [TAS]
- negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [IMP]
- positive regulation of cell proliferation [IMP]
- regulation of insulin secretion [TAS]
- small molecule metabolic process [TAS]
- transport [TAS]
- viral process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
TRIM6 promotes colorectal cancer cells proliferation and response to thiostrepton by TIS21/FoxM1.
Tripartite motif-containing proteins (TRIM) play a crucial role in carcinogenesis. Little attention has been focused on the possible functions of TRIM6 on carcinogenesis.The expression levels of TRIM6 were assessed in colorectal cancer (CRC) samples. TRIM6 expression was knocked down in CRC cell lines, and subjected to Cell counting kit-8 (CCK-8), bromodeoxyuridine (BrdU) incorporation and cell cycle assays. Immunoprecipitation and proteomics ... [more]
J. Exp. Clin. Cancer Res. Jan. 28, 2020; 39(1);23 [Pubmed: 31992359]
Throughput
- High Throughput
Curated By
- BioGRID