BAIT
MECR
CGI-63, FASN2B, NRBF1, RP11-467D18.1
mitochondrial trans-2-enoyl-CoA reductase
GO Process (1)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
RXRA
9530071D11Rik, Nr2b1, RXRalpha1, RP23-413I12.1
retinoid X receptor alpha
GO Process (34)
GO Function (19)
GO Component (5)
Gene Ontology Biological Process
- angiogenesis involved in coronary vascular morphogenesis [TAS]
- camera-type eye development [IGI]
- cardiac muscle cell differentiation [TAS]
- cardiac muscle cell proliferation [IGI, IMP, TAS]
- embryo implantation [IGI]
- heart development [IMP, TAS]
- heart morphogenesis [TAS]
- in utero embryonic development [IGI]
- maternal placenta development [IGI]
- mesenchyme development [TAS]
- modulation by virus of host morphology or physiology [ISO]
- negative regulation of cell proliferation [ISO]
- negative regulation of gene expression [TAS]
- negative regulation of transcription from RNA polymerase II promoter [IGI, ISO]
- peroxisome proliferator activated receptor signaling pathway [ISO]
- placenta development [IMP]
- positive regulation of apoptotic process [ISO]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IGI, IMP, ISO]
- positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [IDA]
- positive regulation of transcription, DNA-templated [IGI, TAS]
- positive regulation of translational initiation by iron [IGI]
- protein homotetramerization [ISO]
- regulation of branching involved in prostate gland morphogenesis [IMP]
- regulation of myelination [ISO]
- regulation of transcription from RNA polymerase II promoter [IGI]
- regulation of transcription, DNA-templated [IDA, ISO]
- response to glucocorticoid [ISO]
- response to retinoic acid [ISO]
- retinoic acid receptor signaling pathway [IDA, IMP, ISO]
- secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [IMP]
- transcription from RNA polymerase II promoter [IDA]
- ventricular cardiac muscle cell differentiation [IGI, IMP]
- ventricular cardiac muscle tissue morphogenesis [IMP]
- visceral serous pericardium development [TAS]
Gene Ontology Molecular Function- 9-cis retinoic acid receptor activity [IDA]
- DNA binding [IDA, IPI, ISO]
- RNA polymerase II regulatory region sequence-specific DNA binding [ISO]
- chromatin DNA binding [IDA]
- double-stranded DNA binding [ISO]
- enzyme binding [ISO]
- ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity [IDA, ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- protein domain specific binding [ISO]
- protein heterodimerization activity [IPI, ISO]
- retinoic acid receptor binding [ISO]
- retinoic acid-responsive element binding [ISO]
- sequence-specific DNA binding [IGI, ISO]
- sequence-specific DNA binding transcription factor activity [IGI, ISO]
- transcription factor binding [IPI]
- transcription regulatory region DNA binding [IDA, ISO]
- vitamin D receptor binding [ISO]
- vitamin D response element binding [ISO]
- 9-cis retinoic acid receptor activity [IDA]
- DNA binding [IDA, IPI, ISO]
- RNA polymerase II regulatory region sequence-specific DNA binding [ISO]
- chromatin DNA binding [IDA]
- double-stranded DNA binding [ISO]
- enzyme binding [ISO]
- ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity [IDA, ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- protein domain specific binding [ISO]
- protein heterodimerization activity [IPI, ISO]
- retinoic acid receptor binding [ISO]
- retinoic acid-responsive element binding [ISO]
- sequence-specific DNA binding [IGI, ISO]
- sequence-specific DNA binding transcription factor activity [IGI, ISO]
- transcription factor binding [IPI]
- transcription regulatory region DNA binding [IDA, ISO]
- vitamin D receptor binding [ISO]
- vitamin D response element binding [ISO]
Gene Ontology Cellular Component
Mus musculus
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Nuclear receptor binding factor-1 (NRBF-1), a protein interacting with a wide spectrum of nuclear hormone receptors.
To identify the proteins which may modulate the functions of peroxisome proliferator-activated receptor (PPAR), a rat liver cDNA library was screened by a yeast two-hybrid system, using the mouse PPARalpha as a bait. A protein named nuclear receptor binding factor-1 (NRBF-1) was identified, which interacts not only with PPARalpha, but also with various nuclear hormone receptors in the presence of ... [more]
Gene Oct. 23, 1998; 221(2);225-33 [Pubmed: 9795230]
Throughput
- Low Throughput
Curated By
- BioGRID