BAIT
GJA1
AVSD3, CMDR, CX43, GJAL, HLHS1, HSS, ODDD
gap junction protein, alpha 1, 43kDa
GO Process (11)
GO Function (4)
GO Component (11)
Gene Ontology Biological Process
- atrial cardiac muscle cell action potential [TAS]
- cell communication by electrical coupling [IDA]
- cell-cell signaling [TAS]
- gap junction assembly [TAS]
- heart development [TAS]
- ion transmembrane transport [TAS]
- membrane organization [TAS]
- muscle contraction [TAS]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [IMP]
- signal transduction [IMP]
- transport [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Golgi apparatus [ISS]
- Golgi membrane [TAS]
- Golgi-associated vesicle membrane [TAS]
- endoplasmic reticulum membrane [TAS]
- extracellular vesicular exosome [IDA]
- focal adhesion [IDA]
- gap junction [IDA, ISS]
- integral component of plasma membrane [TAS]
- intercalated disc [IDA, ISS]
- membrane raft [ISS]
- plasma membrane [ISS, TAS]
Homo sapiens
PREY
GJA5
ATFB11, CX40
gap junction protein, alpha 5, 40kDa
GO Process (15)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
- AV node cell to bundle of His cell communication by electrical coupling [IMP]
- angiogenesis [IEP]
- artery morphogenesis [ISS]
- atrial cardiac muscle cell action potential [IMP]
- atrial septum development [IMP]
- bundle of His cell to Purkinje myocyte communication [IMP]
- cell communication by electrical coupling involved in cardiac conduction [IDA]
- gap junction assembly [IDA, IMP]
- mitral valve development [IMP]
- outflow tract morphogenesis [IMP]
- pulmonary valve formation [IMP]
- regulation of atrial cardiac muscle cell membrane depolarization [IMP]
- regulation of cardiac muscle contraction [IMP]
- transmembrane transport [IDA]
- ventricular septum development [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-purification
An interaction is inferred from the identification of two or more protein subunits in a purified protein complex, as obtained by classical biochemical fractionation or affinity purification and one or more additional fractionation steps.
Publication
Gap junction channels formed by coexpressed connexin40 and connexin43.
Many cardiovascular cells coexpress multiple connexins (Cx), leading to the potential formation of mixed (heteromeric) gap junction hemichannels whose biophysical properties may differ from homomeric channels containing only one connexin type. We examined the potential interaction of connexin Cx43 and Cx40 in HeLa cells sequentially stably transfected with these two connexins. Immunoblots verified the production of comparable amounts of both ... [more]
Am. J. Physiol. Heart Circ. Physiol. Oct. 01, 2001; 281(4);H1675-89 [Pubmed: 11557558]
Throughput
- Low Throughput
Curated By
- BioGRID