BAIT

RPS27

3200001M24Rik
ribosomal protein S27
GO Process (0)
GO Function (1)
GO Component (0)

Gene Ontology Molecular Function

Mus musculus
PREY

RPL7A

Surf3, RP23-414L19.4
ribosomal protein L7A
GO Process (0)
GO Function (2)
GO Component (6)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Mus musculus

Co-fractionation

Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.

Publication

The E3 ubiquitin ligase UBR5 interacts with the H/ACA ribonucleoprotein complex and regulates ribosomal RNA biogenesis in embryonic stem cells.

Saez I, Gerbracht JV, Koyuncu S, Lee HJ, Horn M, Kroef V, Denzel MS, Dieterich C, Gehring NH, Vilchez D

UBR5 is an E3 ubiquitin ligase involved in distinct processes such as transcriptional regulation and development. UBR5 is highly upregulated in embryonic stem cells (ESCs), whereas its expression decreases with differentiation, suggesting a role for UBR5 in ESC function. However, little is known about how UBR5 regulates ESC identity. Here, we define the protein interactome of UBR5 in ESCs and ... [more]

FEBS Lett. Dec. 01, 2019; 594(1);175-188 [Pubmed: 31365120]

Throughput

  • Low Throughput

Curated By

  • BioGRID