BAIT
CIT
CRIK, STK21
citron rho-interacting serine/threonine kinase
GO Process (4)
GO Function (3)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
PID1
NYGGF4, P-CLI1, PCLI1, HMFN2073
phosphotyrosine interaction domain containing 1
GO Process (22)
GO Function (0)
GO Component (2)
Gene Ontology Biological Process
- cellular response to cytokine stimulus [ISS]
- cellular response to fatty acid [ISS]
- cellular response to interleukin-6 [ISS]
- cellular response to tumor necrosis factor [ISS, NAS]
- energy reserve metabolic process [IC]
- fat cell differentiation [IDA]
- mitochondrion morphogenesis [IMP]
- negative regulation of ATP biosynthetic process [IMP]
- negative regulation of establishment of protein localization to plasma membrane [IDA]
- negative regulation of glucose import in response to insulin stimulus [IDA]
- negative regulation of insulin receptor signaling pathway [IDA]
- negative regulation of mitochondrial DNA replication [IMP]
- negative regulation of protein phosphorylation [IDA]
- positive regulation of ATP biosynthetic process [ISS]
- positive regulation of fat cell proliferation [IDA]
- positive regulation of gene expression [IMP]
- positive regulation of reactive oxygen species metabolic process [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IMP]
- regulation of G1/S transition of mitotic cell cycle [IDA]
- regulation of mitochondrial fusion [IC]
- regulation of mitochondrial membrane potential [ISS, TAS]
- regulation of reactive oxygen species metabolic process [ISS]
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis.
The midbody is an organelle assembled at the intercellular bridge between the two daughter cells at the end of mitosis. It controls the final separation of the daughter cells and has been involved in cell fate, polarity, tissue organization, and cilium and lumen formation. Here, we report the characterization of the intricate midbody protein-protein interaction network (interactome), which identifies many ... [more]
Unknown Dec. 04, 2018; 10(1);4513 [Pubmed: 31586073]
Throughput
- High Throughput
Curated By
- BioGRID