BAIT
CIT
CRIK, STK21
citron rho-interacting serine/threonine kinase
GO Process (4)
GO Function (3)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
ASPH
AAH, BAH, CASQ2BP1, FDLAB, HAAH, JCTN, junctin
aspartate beta-hydroxylase
GO Process (17)
GO Function (6)
GO Component (9)
Gene Ontology Biological Process
- activation of cysteine-type endopeptidase activity [IDA]
- activation of store-operated calcium channel activity [IDA]
- calcium ion transmembrane transport [IDA]
- cellular response to calcium ion [IDA]
- detection of calcium ion [TAS]
- muscle contraction [TAS]
- positive regulation of calcium ion transport into cytosol [IDA]
- positive regulation of intracellular protein transport [IDA]
- positive regulation of proteolysis [IDA]
- positive regulation of ryanodine-sensitive calcium-release channel activity [TAS]
- positive regulation of transcription, DNA-templated [IMP]
- regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [ISS, TAS]
- regulation of cell communication by electrical coupling [TAS]
- regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [IDA]
- regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [TAS]
- regulation of ryanodine-sensitive calcium-release channel activity [TAS]
- response to ATP [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- calcium channel complex [TAS]
- cortical endoplasmic reticulum [IDA]
- endoplasmic reticulum [IDA]
- endoplasmic reticulum membrane [NAS]
- integral component of endoplasmic reticulum membrane [IDA]
- junctional sarcoplasmic reticulum membrane [TAS]
- plasma membrane [IDA]
- sarcoplasmic reticulum lumen [TAS]
- sarcoplasmic reticulum membrane [TAS]
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis.
The midbody is an organelle assembled at the intercellular bridge between the two daughter cells at the end of mitosis. It controls the final separation of the daughter cells and has been involved in cell fate, polarity, tissue organization, and cilium and lumen formation. Here, we report the characterization of the intricate midbody protein-protein interaction network (interactome), which identifies many ... [more]
Unknown Dec. 04, 2018; 10(1);4513 [Pubmed: 31586073]
Throughput
- High Throughput
Curated By
- BioGRID