BAIT
CIT
CRIK, STK21
citron rho-interacting serine/threonine kinase
GO Process (4)
GO Function (3)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
MCU
C10orf42, CCDC109A
mitochondrial calcium uniporter
GO Process (7)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
- calcium ion transmembrane import into mitochondrion [IDA]
- calcium-mediated signaling [IDA]
- glucose homeostasis [IMP]
- mitochondrial calcium ion transport [IDA, IMP]
- positive regulation of insulin secretion [IMP]
- positive regulation of mitochondrial calcium ion concentration [IDA, IMP]
- protein complex oligomerization [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis.
The midbody is an organelle assembled at the intercellular bridge between the two daughter cells at the end of mitosis. It controls the final separation of the daughter cells and has been involved in cell fate, polarity, tissue organization, and cilium and lumen formation. Here, we report the characterization of the intricate midbody protein-protein interaction network (interactome), which identifies many ... [more]
Unknown Dec. 04, 2018; 10(1);4513 [Pubmed: 31586073]
Throughput
- High Throughput
Curated By
- BioGRID