BAIT
LTB4R2
BLT2, BLTR2, JULF2, KPG_004, LTB4-R 2, LTB4-R2, NOP9
leukotriene B4 receptor 2
GO Process (2)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
DDOST
AGER1, CDG1R, OKSWcl45, OST, OST48, WBP1, OK/SW-cl.45
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
GO Process (11)
GO Function (3)
GO Component (6)
Gene Ontology Biological Process
- SRP-dependent cotranslational protein targeting to membrane [TAS]
- T cell activation [IDA]
- cellular protein metabolic process [TAS]
- gene expression [TAS]
- innate immune response [TAS]
- post-translational protein modification [TAS]
- protein N-linked glycosylation [IDA]
- protein N-linked glycosylation via asparagine [IC, TAS]
- protein glycosylation [ISS]
- response to cytokine [IDA]
- translation [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Systematic protein-protein interaction mapping for clinically relevant human GPCRs.
G-protein-coupled receptors (GPCRs) are the largest family of integral membrane receptors with key roles in regulating signaling pathways targeted by therapeutics, but are difficult to study using existing proteomics technologies due to their complex biochemical features. To obtain a global view of GPCR-mediated signaling and to identify novel components of their pathways, we used a modified membrane yeast two-hybrid (MYTH) ... [more]
Mol. Syst. Biol. Dec. 15, 2016; 13(3);918 [Pubmed: 28298427]
Throughput
- High Throughput
Additional Notes
- interaction identified using a modified split-ubiquitin membrane yeast two-hybrid (MYTH) assay
Curated By
- BioGRID