BAIT
ECT2
ARHGEF31
epithelial cell transforming 2
GO Process (22)
GO Function (5)
GO Component (11)
Gene Ontology Biological Process
- activation of Rac GTPase activity [IMP]
- activation of Rho GTPase activity [IDA]
- activation of protein kinase activity [IDA]
- apoptotic signaling pathway [TAS]
- cellular response to calcium ion [IDA]
- cellular response to hydrogen peroxide [IDA]
- cellular response to ionizing radiation [IDA]
- cytokinesis [IMP]
- neurotrophin TRK receptor signaling pathway [TAS]
- positive regulation of Cdc42 GTPase activity [IDA]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [IMP]
- positive regulation of Rho GTPase activity [IDA, IMP]
- positive regulation of apoptotic process [IDA, TAS]
- positive regulation of cytokinesis [IDA, IMP]
- positive regulation of neuron differentiation [ISS]
- positive regulation of protein import into nucleus [ISS]
- protein homooligomerization [IDA]
- regulation of attachment of spindle microtubules to kinetochore [IMP]
- regulation of protein kinase activity [IDA]
- regulation of small GTPase mediated signal transduction [TAS]
- small GTPase mediated signal transduction [TAS]
- tight junction assembly [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
MYO1C
MMI-beta, MMIb, NMI, myr2
myosin IC
GO Process (10)
GO Function (2)
GO Component (14)
Gene Ontology Biological Process
- Fc-gamma receptor signaling pathway involved in phagocytosis [TAS]
- innate immune response [TAS]
- membrane organization [TAS]
- positive regulation of cell migration [IMP]
- positive regulation of cell migration by vascular endothelial growth factor signaling pathway [IMP]
- positive regulation of protein targeting to membrane [IMP]
- positive regulation of vascular endothelial growth factor signaling pathway [IMP]
- protein targeting [IDA]
- protein targeting to membrane [IDA]
- regulation of tight junction assembly [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- basal plasma membrane [IDA]
- cytoplasm [IDA]
- cytosol [TAS]
- extracellular vesicular exosome [IDA]
- filamentous actin [IDA]
- lateral plasma membrane [IDA]
- membrane [IDA]
- membrane raft [IDA]
- microvillus [IDA]
- mitochondrion [IDA]
- nucleoplasm [IDA]
- plasma membrane [IDA]
- stress fiber [IDA]
- unconventional myosin complex [TAS]
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis.
The midbody is an organelle assembled at the intercellular bridge between the two daughter cells at the end of mitosis. It controls the final separation of the daughter cells and has been involved in cell fate, polarity, tissue organization, and cilium and lumen formation. Here, we report the characterization of the intricate midbody protein-protein interaction network (interactome), which identifies many ... [more]
Unknown Dec. 04, 2018; 10(1);4513 [Pubmed: 31586073]
Throughput
- High Throughput
Curated By
- BioGRID