BAIT
KIF14
kinesin family member 14
GO Process (32)
GO Function (9)
GO Component (6)
Gene Ontology Biological Process
- ATP catabolic process [IBA, ISS]
- SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [IMP]
- activation of protein kinase activity [IMP]
- cell proliferation in forebrain [ISS]
- cerebellar Purkinje cell layer structural organization [ISS]
- cerebellar cortex development [ISS]
- cerebellar granular layer structural organization [ISS]
- cerebral cortex development [ISS]
- cytoskeleton-dependent intracellular transport [IBA]
- establishment of protein localization [IDA]
- hippocampus development [ISS]
- microtubule depolymerization [ISS]
- microtubule-based movement [IBA]
- mitotic cell cycle process [IMP]
- mitotic metaphase plate congression [IMP]
- negative regulation of apoptotic process [IMP]
- negative regulation of integrin activation [IMP]
- negative regulation of neuron apoptotic process [ISS]
- olfactory bulb development [ISS]
- positive regulation of cell proliferation [IDA, IMP]
- positive regulation of cytokinesis [IMP]
- proteasome-mediated ubiquitin-dependent protein catabolic process [IMP]
- regulation of G1/S transition of mitotic cell cycle [IMP]
- regulation of G2/M transition of mitotic cell cycle [IMP]
- regulation of Rap protein signal transduction [IMP]
- regulation of cell adhesion [IMP]
- regulation of cell growth [IMP]
- regulation of cell migration [IMP]
- regulation of myelination [ISS]
- regulation of neuron apoptotic process [ISS]
- response to docetaxel trihydrate [IMP]
- substrate adhesion-dependent cell spreading [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
PAK2
PAK65, PAKgamma
p21 protein (Cdc42/Rac)-activated kinase 2
GO Process (24)
GO Function (7)
GO Component (4)
Gene Ontology Biological Process
- Fc-epsilon receptor signaling pathway [TAS]
- T cell costimulation [TAS]
- T cell receptor signaling pathway [TAS]
- apoptotic process [TAS]
- axon guidance [TAS]
- cellular component disassembly involved in execution phase of apoptosis [TAS]
- innate immune response [TAS]
- intracellular signal transduction [IBA]
- mitotic cell cycle [IBA]
- negative regulation of apoptotic process [IMP, TAS]
- negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis [IDA]
- negative regulation of protein kinase activity [TAS]
- peptidyl-serine phosphorylation [IDA]
- phosphorylation [IDA]
- positive regulation of extrinsic apoptotic signaling pathway [IMP]
- positive regulation of peptidyl-tyrosine phosphorylation [IDA]
- positive regulation of protein tyrosine kinase activity [IDA]
- protein autophosphorylation [IDA]
- protein phosphorylation [IDA]
- regulation of apoptotic process [TAS]
- regulation of defense response to virus by virus [TAS]
- signal transduction [TAS]
- signal transduction by phosphorylation [IBA]
- viral process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis.
The midbody is an organelle assembled at the intercellular bridge between the two daughter cells at the end of mitosis. It controls the final separation of the daughter cells and has been involved in cell fate, polarity, tissue organization, and cilium and lumen formation. Here, we report the characterization of the intricate midbody protein-protein interaction network (interactome), which identifies many ... [more]
Unknown Dec. 04, 2018; 10(1);4513 [Pubmed: 31586073]
Throughput
- High Throughput
Curated By
- BioGRID