BAIT
KIF14
kinesin family member 14
GO Process (32)
GO Function (9)
GO Component (6)
Gene Ontology Biological Process
- ATP catabolic process [IBA, ISS]
- SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [IMP]
- activation of protein kinase activity [IMP]
- cell proliferation in forebrain [ISS]
- cerebellar Purkinje cell layer structural organization [ISS]
- cerebellar cortex development [ISS]
- cerebellar granular layer structural organization [ISS]
- cerebral cortex development [ISS]
- cytoskeleton-dependent intracellular transport [IBA]
- establishment of protein localization [IDA]
- hippocampus development [ISS]
- microtubule depolymerization [ISS]
- microtubule-based movement [IBA]
- mitotic cell cycle process [IMP]
- mitotic metaphase plate congression [IMP]
- negative regulation of apoptotic process [IMP]
- negative regulation of integrin activation [IMP]
- negative regulation of neuron apoptotic process [ISS]
- olfactory bulb development [ISS]
- positive regulation of cell proliferation [IDA, IMP]
- positive regulation of cytokinesis [IMP]
- proteasome-mediated ubiquitin-dependent protein catabolic process [IMP]
- regulation of G1/S transition of mitotic cell cycle [IMP]
- regulation of G2/M transition of mitotic cell cycle [IMP]
- regulation of Rap protein signal transduction [IMP]
- regulation of cell adhesion [IMP]
- regulation of cell growth [IMP]
- regulation of cell migration [IMP]
- regulation of myelination [ISS]
- regulation of neuron apoptotic process [ISS]
- response to docetaxel trihydrate [IMP]
- substrate adhesion-dependent cell spreading [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
NEDD4L
NEDD4-2, NEDD4.2, RSP5, hNEDD4-2
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
GO Process (33)
GO Function (7)
GO Component (7)
Gene Ontology Biological Process
- cellular sodium ion homeostasis [NAS]
- excretion [NAS]
- gene expression [TAS]
- ion transmembrane transport [TAS]
- negative regulation of potassium ion transmembrane transport [IDA]
- negative regulation of potassium ion transmembrane transporter activity [IDA]
- negative regulation of protein localization to cell surface [IDA]
- negative regulation of sodium ion transmembrane transport [IDA]
- negative regulation of sodium ion transmembrane transporter activity [IDA]
- negative regulation of transcription from RNA polymerase II promoter [TAS]
- negative regulation of transforming growth factor beta receptor signaling pathway [TAS]
- positive regulation of caveolin-mediated endocytosis [ISS]
- positive regulation of endocytosis [NAS]
- proteasome-mediated ubiquitin-dependent protein catabolic process [IDA]
- protein K48-linked ubiquitination [IDA]
- protein ubiquitination [IDA, NAS]
- protein ubiquitination involved in ubiquitin-dependent protein catabolic process [IBA, IDA]
- regulation of ion transmembrane transport [IDA]
- regulation of membrane depolarization [IDA]
- regulation of membrane potential [IDA]
- regulation of membrane repolarization [IDA]
- regulation of potassium ion transmembrane transporter activity [IDA]
- regulation of protein catabolic process [NAS]
- response to metal ion [IDA]
- sodium ion transport [NAS]
- transcription initiation from RNA polymerase II promoter [TAS]
- transcription, DNA-templated [TAS]
- transforming growth factor beta receptor signaling pathway [TAS]
- transmembrane transport [TAS]
- ventricular cardiac muscle cell action potential [ISS]
- viral life cycle [TAS]
- viral process [TAS]
- water homeostasis [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis.
The midbody is an organelle assembled at the intercellular bridge between the two daughter cells at the end of mitosis. It controls the final separation of the daughter cells and has been involved in cell fate, polarity, tissue organization, and cilium and lumen formation. Here, we report the characterization of the intricate midbody protein-protein interaction network (interactome), which identifies many ... [more]
Unknown Dec. 04, 2018; 10(1);4513 [Pubmed: 31586073]
Throughput
- High Throughput
Curated By
- BioGRID