BAIT
SUMO2
HSMT3, SMT3B, SMT3H2, SUMO3, Smt3A
small ubiquitin-like modifier 2
GO Process (4)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
KIF2C
CT139, KNSL6, MCAK, RP11-269F19.1
kinesin family member 2C
GO Process (12)
GO Function (5)
GO Component (8)
Gene Ontology Biological Process
- ATP catabolic process [IBA]
- antigen processing and presentation of exogenous peptide antigen via MHC class II [TAS]
- blood coagulation [TAS]
- cell proliferation [TAS]
- establishment or maintenance of microtubule cytoskeleton polarity [IMP]
- metabolic process [IBA, TAS]
- microtubule depolymerization [IDA, IMP]
- microtubule-based movement [IBA, TAS]
- mitotic cell cycle [TAS]
- mitotic metaphase plate congression [IMP]
- mitotic nuclear division [TAS]
- regulation of chromosome segregation [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.
Post-translational modification with the small ubiquitin-like modifier (SUMO) affects thousands of proteins in the human proteome and is implicated in numerous cellular processes. The main outcome of SUMO conjugation is a rewiring of protein-protein interactions through recognition of the modifier's surface by SUMO binding proteins. The SUMO-interacting motif (SIM) mediates binding to a groove on SUMO; however, the low affinity ... [more]
ACS Chem Biol Dec. 18, 2019; 15(9);2406-2414 [Pubmed: 32786267]
Throughput
- High Throughput
Additional Notes
- #LPPI
- Likely protein-protein interaction
Curated By
- BioGRID