BAIT

NRBF2

COPR1, COPR2, NRBF-2, RP11-144G16.2
nuclear receptor binding factor 2
GO Process (2)
GO Function (0)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Cellular Component

Homo sapiens
PREY

THRB

C-ERBA-2, C-ERBA-BETA, ERBA2, GRTH, NR1A2, PRTH, THR1, THRB1, THRB2
thyroid hormone receptor, beta
Homo sapiens

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

Nuclear receptor binding factor-2 (NRBF-2), a possible gene activator protein interacting with nuclear hormone receptors.

Yasumo H, Masuda N, Furusawa T, Tsukamoto T, Sadano H, Osumi T

A protein named nuclear receptor binding factor-2 (NRBF-2) was identified by yeast two-hybrid screening, as an interaction partner of peroxisome proliferator-activated receptor alpha as well as several other nuclear receptors. NRBF-2 exhibited a gene activation function, when tethered to a heterologous DNA binding domain, in both mammalian cells and yeast. ... [more]

Biochim. Biophys. Acta Jan. 31, 2000; 1490(1);189-97 [Pubmed: 10786636]

Throughput

  • Low Throughput

Curated By

  • BioGRID