PREY
KEAP1
INrf2, KLHL19
kelch-like ECH-associated protein 1
GO Process (4)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Protein-peptide
An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.
Publication
A Case Study on the Keap1 Interaction with Peptide Sequence Epitopes Selected by the Peptidomic mRNA Display.
Many protein-protein and peptide-protein interactions (PPIs) play key roles in the regulation of biological functions, and therefore, the modulation of PPIs has become an attractive target of new drug development. Although a number of PPIs have already been identified, over 100?000 unknown PPIs are predicted to exist. To uncover such unknown PPIs, it is important to devise a conceptually distinct ... [more]
Chembiochem Dec. 16, 2018; 20(16);2089-2100 [Pubmed: 31169361]
Throughput
- Low Throughput
Additional Notes
- biotin-labeled bait peptides were mixed with cell lysates, isolated, and associated Keap1 hit protein was identified by western blot
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| KEAP1 ASTN1 | Protein-peptide Protein-peptide An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments. | High | - | BioGRID | 2909631 | |
| ASTN1 KEAP1 | Reconstituted Complex Reconstituted Complex An interaction is detected between purified proteins in vitro. | Low | - | BioGRID | 2909636 |
Curated By
- BioGRID