PREY
KEAP1
INrf2, KLHL19
kelch-like ECH-associated protein 1
GO Process (4)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
A Case Study on the Keap1 Interaction with Peptide Sequence Epitopes Selected by the Peptidomic mRNA Display.
Many protein-protein and peptide-protein interactions (PPIs) play key roles in the regulation of biological functions, and therefore, the modulation of PPIs has become an attractive target of new drug development. Although a number of PPIs have already been identified, over 100?000 unknown PPIs are predicted to exist. To uncover such unknown PPIs, it is important to devise a conceptually distinct ... [more]
Chembiochem Dec. 16, 2018; 20(16);2089-2100 [Pubmed: 31169361]
Throughput
- Low Throughput
Additional Notes
- assayed using SPR (surface plasmon resonance) with peptides derived from the bait proteins immobilized on the SPR membrane resulting in the identification of the hit protein from cell lysates
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| KEAP1 ASTN1 | Protein-peptide Protein-peptide An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments. | High | - | BioGRID | 2909631 | |
| ASTN1 KEAP1 | Protein-peptide Protein-peptide An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments. | Low | - | BioGRID | 2909634 |
Curated By
- BioGRID