BAIT
TXNIP
EST01027, HHCPA78, THIF, VDUP1, RP11-315I20.4
thioredoxin interacting protein
GO Process (5)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
EIF4B
EIF-4B, PRO1843
eukaryotic translation initiation factor 4B
GO Process (10)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- cellular protein metabolic process [TAS]
- gene expression [TAS]
- insulin receptor signaling pathway [TAS]
- mRNA metabolic process [TAS]
- nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [TAS]
- nuclear-transcribed mRNA poly(A) tail shortening [TAS]
- regulation of translational initiation [TAS]
- translation [TAS]
- translational initiation [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Thioredoxin interacting protein (Txnip) forms redox sensitive high molecular weight nucleoprotein complexes.
Thioredoxin interacting protein (Txnip) is an ?-arrestin protein that regulates pleiotropic biological responses. Txnip acts as a cancer suppressor and is a critical regulator of energy metabolism. To investigate molecular mechanisms involving Txnip, we searched for its protein binding partners using tandem affinity purification and proteomics analyses and identified several viable candidates, including HSP90, HSP70, and Prp31. We showed, by ... [more]
Arch Biochem Biophys Dec. 30, 2018; 677();108159 [Pubmed: 31669268]
Throughput
- High Throughput
Curated By
- BioGRID