BAIT
DDRGK1
C20orf116, UFBP1, dJ1187M17.3
DDRGK domain containing 1
GO Process (1)
GO Function (2)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
SDCBP
MDA-9, MDA9, ST1, SYCL, TACIP18
syndecan binding protein (syntenin)
GO Process (10)
GO Function (8)
GO Component (12)
Gene Ontology Biological Process
- actin cytoskeleton organization [NAS]
- axon guidance [TAS]
- intracellular signal transduction [NAS]
- positive regulation of JNK cascade [IC]
- positive regulation of exosomal secretion [IMP]
- positive regulation of extracellular vesicular exosome assembly [IMP]
- positive regulation of phosphorylation [IDA]
- protein targeting to membrane [NAS]
- substrate-dependent cell migration, cell extension [NAS]
- synaptic transmission [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
UFMylation maintains tumour suppressor p53 stability by antagonizing its ubiquitination.
p53 is the most intensively studied tumour suppressor1. The regulation of p53 homeostasis is essential for its tumour-suppressive function2,3. Although p53 is regulated by an array of post-translational modifications, both during normal homeostasis and in stress-induced responses2-4, how p53 maintains its homeostasis remains unclear. UFMylation is a recently identified ubiquitin-like modification with essential biological functions5-7. Deficiency in this modification leads ... [more]
Nat Cell Biol Dec. 01, 2019; 22(9);1056-1063 [Pubmed: 32807901]
Throughput
- High Throughput
Curated By
- BioGRID