RHOB
Gene Ontology Biological Process
- GTP catabolic process [TAS]
- Rho protein signal transduction [TAS]
- apoptotic process [TAS]
- axon guidance [TAS]
- blood coagulation [TAS]
- cell adhesion [ISS]
- cellular response to hydrogen peroxide [IDA]
- cellular response to ionizing radiation [IDA]
- cytokinesis [IMP]
- endosome to lysosome transport [IDA]
- negative regulation of cell cycle [ISS]
- platelet activation [TAS]
- positive regulation of angiogenesis [ISS]
- positive regulation of apoptotic process [IMP]
- regulation of small GTPase mediated signal transduction [TAS]
- small GTPase mediated signal transduction [TAS]
- transformed cell apoptotic process [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
SLC26A6
Gene Ontology Biological Process
- angiotensin-activated signaling pathway [IDA]
- anion transport [IDA]
- bicarbonate transport [IDA, IMP]
- cellular response to cAMP [ISS]
- cellular response to fructose stimulus [ISS]
- cellular response to interferon-gamma [IDA]
- chloride transmembrane transport [IDA, IMP, ISS]
- chloride transport [IDA, IMP]
- epithelial fluid transport [ISS]
- formate transport [ISS]
- intestinal absorption [ISS]
- intracellular pH elevation [ISS]
- ion transport [TAS]
- mannitol transport [ISS]
- oxalate transport [IMP, ISS]
- oxalic acid secretion [ISS]
- positive regulation of dipeptide transmembrane transport [ISS]
- protein kinase C signaling [IDA]
- regulation of intracellular pH [IDA, IMP]
- sperm capacitation [ISS]
- sulfate transmembrane transport [IDA, IMP]
- sulfate transport [IMP, ISS]
- transepithelial chloride transport [IMP, ISS]
- transepithelial transport [ISS]
- transmembrane transport [TAS]
Gene Ontology Molecular Function- PDZ domain binding [ISS]
- anion:anion antiporter activity [IDA, IMP, ISS]
- bicarbonate transmembrane transporter activity [IDA, IMP, ISS]
- chloride transmembrane transporter activity [IDA, IMP, ISS]
- efflux transmembrane transporter activity [ISS]
- formate efflux transmembrane transporter activity [ISS]
- formate transmembrane transporter activity [ISS]
- formate uptake transmembrane transporter activity [ISS]
- oxalate transmembrane transporter activity [IMP]
- protein binding [IPI]
- sulfate transmembrane transporter activity [IDA, IMP]
- PDZ domain binding [ISS]
- anion:anion antiporter activity [IDA, IMP, ISS]
- bicarbonate transmembrane transporter activity [IDA, IMP, ISS]
- chloride transmembrane transporter activity [IDA, IMP, ISS]
- efflux transmembrane transporter activity [ISS]
- formate efflux transmembrane transporter activity [ISS]
- formate transmembrane transporter activity [ISS]
- formate uptake transmembrane transporter activity [ISS]
- oxalate transmembrane transporter activity [IMP]
- protein binding [IPI]
- sulfate transmembrane transporter activity [IDA, IMP]
Gene Ontology Cellular Component
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
A proximity-dependent biotinylation map of a human cell.
Compartmentalization is a defining characteristic of eukaryotic cells, and partitions distinct biochemical processes into discrete subcellular locations. Microscopy1 and biochemical fractionation coupled with mass spectrometry2-4 have defined the proteomes of a variety of different organelles, but many intracellular compartments have remained refractory to such approaches. Proximity-dependent biotinylation techniques such as BioID provide an alternative approach to define the composition of ... [more]
Quantitative Score
- 35.0 [FoldChange]
Throughput
- High Throughput
Additional Notes
- BioID
- SAINTexpress (v.3.6.1) was used to identify proximity interactions and those with a Bayesian FDR =< 0.01 were considered high confidence. The score represents the fold change of the average spectral count in sample replicates relative to the average in control replicates.
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| RHOB SLC26A6 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | Low | - | BioGRID | 3334100 |
Curated By
- BioGRID