PIK3CB
Gene Ontology Biological Process
- Fc-epsilon receptor signaling pathway [TAS]
- Fc-gamma receptor signaling pathway involved in phagocytosis [TAS]
- G-protein coupled receptor signaling pathway [TAS]
- T cell receptor signaling pathway [TAS]
- activation of MAPK activity [TAS]
- blood coagulation [TAS]
- cell migration [TAS]
- chemotaxis [TAS]
- epidermal growth factor receptor signaling pathway [TAS]
- fibroblast growth factor receptor signaling pathway [TAS]
- innate immune response [TAS]
- insulin receptor signaling pathway [TAS]
- leukocyte migration [TAS]
- neurotrophin TRK receptor signaling pathway [TAS]
- phosphatidylinositol 3-kinase signaling [TAS]
- phosphatidylinositol biosynthetic process [TAS]
- phosphatidylinositol-mediated signaling [TAS]
- phospholipid metabolic process [TAS]
- platelet activation [TAS]
- platelet aggregation [TAS]
- positive regulation of autophagy [TAS]
- regulation of clathrin-mediated endocytosis [TAS]
- signal transduction [NAS]
- small molecule metabolic process [TAS]
- transmembrane receptor protein tyrosine kinase signaling pathway [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
PRKCD
Gene Ontology Biological Process
- Fc-gamma receptor signaling pathway involved in phagocytosis [TAS]
- RNA metabolic process [TAS]
- activation of phospholipase C activity [TAS]
- apoptotic process [IDA, TAS]
- blood coagulation [TAS]
- cellular component disassembly involved in execution phase of apoptosis [TAS]
- cellular senescence [IMP]
- cytokine-mediated signaling pathway [TAS]
- defense response to bacterium [ISS]
- epidermal growth factor receptor signaling pathway [TAS]
- fibroblast growth factor receptor signaling pathway [TAS]
- gene expression [TAS]
- innate immune response [TAS]
- interferon-gamma-mediated signaling pathway [TAS]
- intrinsic apoptotic signaling pathway in response to oxidative stress [TAS]
- mRNA metabolic process [TAS]
- negative regulation of MAP kinase activity [IMP]
- negative regulation of actin filament polymerization [ISS]
- negative regulation of filopodium assembly [ISS]
- negative regulation of glial cell apoptotic process [IMP]
- negative regulation of inflammatory response [IC]
- negative regulation of insulin receptor signaling pathway [ISS, TAS]
- negative regulation of peptidyl-tyrosine phosphorylation [ISS]
- negative regulation of platelet aggregation [ISS]
- negative regulation of protein binding [TAS]
- neurotrophin TRK receptor signaling pathway [TAS]
- neutrophil activation [IDA]
- peptidyl-threonine phosphorylation [IDA]
- platelet activation [TAS]
- positive regulation of ceramide biosynthetic process [IMP]
- positive regulation of glucosylceramide catabolic process [IMP]
- positive regulation of phospholipid scramblase activity [IMP]
- positive regulation of protein dephosphorylation [IMP]
- positive regulation of response to DNA damage stimulus [IMP]
- positive regulation of sphingomyelin catabolic process [IMP]
- positive regulation of superoxide anion generation [IMP]
- protein phosphorylation [IDA]
- protein stabilization [NAS]
- regulation of receptor activity [TAS]
- signal transduction [TAS]
- termination of signal transduction [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Physical and functional interactions between protein tyrosine phosphatase alpha, PI 3-kinase, and PKCdelta.
The somatostatin analogue, TT-232 inhibits cell proliferation and induces apoptosis in a variety of tumor cells both in vivo and in vitro. While the early transient activation of Erk/MAPK was found to be important for the induction of cell cycle arrest, the signaling pathway leading to the activation of Erk/MAPK had not been fully established. Here we present evidence that ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID